Need Help?

Get a Free Quote

Tell us what you're looking for and an agent will follow up with pricing.

South America
Destination

Cruises to South America

280 sailings 12 cruise lines
All Months Sep '26 (4) Oct '26 (6) Nov '26 (12) Dec '26 (12) Jan '27 (22) Feb '27 (17) Mar '27 (13) Apr '27 (4) May '27 (6) Jun '27 (4) Jul '27 (3) Aug '27 (1) Sep '27 (4) Oct '27 (14) Nov '27 (14) Dec '27 (14) Jan '28 (28) Feb '28 (19) Mar '28 (8) Apr '28 (5) May '28 (4) Jun '28 (4) Jul '28 (3) Aug '28 (2) Sep '28 (5) Oct '28 (5) Nov '28 (9) Dec '28 (11) Jan '29 (13) Feb '29 (9) Mar '29 (5)
All Sailings 280 Page 1 of 14
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Sep 5 2026
San Cristobal/ECUADOR, Bartolome/san Salvador Isl./ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Fernandia Isl./punta Espinoza/ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Bahia Elizabeth/isabela Isl./EQUADOR, Post Office/floreana Isl./ECUADOR, Punta Cormorant/floreana Isl./EQUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Cerro Brujo, Galapagos Islands, Isla Santa Cruz (Darwin Station), San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Sep 12 2026
San Cristobal/ECUADOR, El Barranco/genovesa Isl./ECUADOR, El Barranco/genovesa Isl./ECUADOR, Isla North Seymour/EQUADOR, Bahia Sullivan/santiago/ECUADOR, Isla Fernandina, Galapagos Islands, Isabela Isl./caleta Tagus/ECUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Bahia Gardner/espanola Isl./EQUADOR, Punta Suarez/espanola/ECUADOR, Cerro Brujo, Galapagos Islands, San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Sep 19 2026
San Cristobal/ECUADOR, Bartolome/san Salvador Isl./ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Fernandia Isl./punta Espinoza/ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Bahia Elizabeth/isabela Isl./EQUADOR, Post Office/floreana Isl./ECUADOR, Punta Cormorant/floreana Isl./EQUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Cerro Brujo, Galapagos Islands, San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Sep 26 2026
San Cristobal/ECUADOR, El Barranco/genovesa Isl./ECUADOR, El Barranco/genovesa Isl./ECUADOR, Isla North Seymour/EQUADOR, Bahia Sullivan/santiago/ECUADOR, Isla Fernandina, Galapagos Islands, Isabela Isl./caleta Tagus/ECUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Bahia Gardner/espanola Isl./EQUADOR, Punta Suarez/espanola/ECUADOR, Cerro Brujo, Galapagos Islands, San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Oct 3 2026
San Cristobal/ECUADOR, Bartolome/san Salvador Isl./ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Fernandia Isl./punta Espinoza/ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Bahia Elizabeth/isabela Isl./EQUADOR, Post Office/floreana Isl./ECUADOR, Punta Cormorant/floreana Isl./EQUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Cerro Brujo, Galapagos Islands, Isla Santa Cruz (Darwin Station), San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Oct 10 2026
San Cristobal/ECUADOR, El Barranco/genovesa Isl./ECUADOR, El Barranco/genovesa Isl./ECUADOR, Isla North Seymour/EQUADOR, Bahia Sullivan/santiago/ECUADOR, Isla Fernandina, Galapagos Islands, Isabela Isl./caleta Tagus/ECUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Bahia Gardner/espanola Isl./EQUADOR, Punta Suarez/espanola/ECUADOR, Cerro Brujo, Galapagos Islands, San Cristobal/ECUADOR
Call for rates
View Details
Seabourn Venture
Onboard Seabourn Venture
16-Night South America Cruise
Barbados → Rio De Janeiro/BRAZIL
Tue, Oct 13 2026
Barbados, Trinidad, Devil's Island/FR. GUIANA, Fortaleza/BRAZIL, Natal/BRAZIL, Salvador De Bahia/BRAZIL, Buzios/BRAZIL, Paraty/BRAZIL, Rio De Janeiro/BRAZIL
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Oct 17 2026
San Cristobal/ECUADOR, Bartolome/san Salvador Isl./ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Fernandia Isl./punta Espinoza/ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Bahia Elizabeth/isabela Isl./EQUADOR, Post Office/floreana Isl./ECUADOR, Punta Cormorant/floreana Isl./EQUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Cerro Brujo, Galapagos Islands, Isla Santa Cruz (Darwin Station), San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Oct 24 2026
San Cristobal/ECUADOR, El Barranco/genovesa Isl./ECUADOR, El Barranco/genovesa Isl./ECUADOR, Isla North Seymour/EQUADOR, Bahia Sullivan/santiago/ECUADOR, Isla Fernandina, Galapagos Islands, Isabela Isl./caleta Tagus/ECUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Bahia Gardner/espanola Isl./EQUADOR, Punta Suarez/espanola/ECUADOR, Cerro Brujo, Galapagos Islands, San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Oct 31 2026
San Cristobal/ECUADOR, Bartolome/san Salvador Isl./ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Fernandia Isl./punta Espinoza/ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Bahia Elizabeth/isabela Isl./EQUADOR, Post Office/floreana Isl./ECUADOR, Punta Cormorant/floreana Isl./EQUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Cerro Brujo, Galapagos Islands, Isla Santa Cruz (Darwin Station), San Cristobal/ECUADOR
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Nov 7 2026
San Cristobal/ECUADOR, El Barranco/genovesa Isl./ECUADOR, El Barranco/genovesa Isl./ECUADOR, Isla North Seymour/EQUADOR, Bahia Sullivan/santiago/ECUADOR, Isla Fernandina, Galapagos Islands, Isabela Isl./caleta Tagus/ECUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Bahia Gardner/espanola Isl./EQUADOR, Punta Suarez/espanola/ECUADOR, Cerro Brujo, Galapagos Islands, San Cristobal/ECUADOR
Call for rates
View Details
Seven Seas Mariner
Onboard Seven Seas Mariner
22-Night South America Cruise
Roundtrip · Miami
Mon, Nov 9 2026
Miami, Barbados, Trinidad, Santarem/BRAZIL, Boca Da Valeria/BRAZIL, Manaus/BRAZIL, Parintins/BRAZIL, Alter Do Chao/BRAZIL, Grenada, San Juan, Miami
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Nov 14 2026
San Cristobal/ECUADOR, Bartolome/san Salvador Isl./ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Fernandia Isl./punta Espinoza/ECUADOR, Isabela Isl./caleta Tagus/ECUADOR, Bahia Elizabeth/isabela Isl./EQUADOR, Post Office/floreana Isl./ECUADOR, Punta Cormorant/floreana Isl./EQUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Cerro Brujo, Galapagos Islands, Isla Santa Cruz (Darwin Station), San Cristobal/ECUADOR
Call for rates
View Details
Oosterdam
Onboard Oosterdam
16-Night South America Cruise
Ft. Lauderdale → San Antonio/CHILE
Wed, Nov 18 2026
Ft. Lauderdale, Grand Cayman, Panama Canal/CRUISING, Panama Canal/CRUISING, Fuerte Amador/PANAMA, Fuerte Amador/PANAMA, Manta/ECUADOR , Salaverry /PERU, Lima/PERU, Lima/PERU, General San Martin/PERU, Coquimbo/CHILE, San Antonio/CHILE
Call for rates
View Details
Oosterdam
Onboard Oosterdam
31-Night South America Cruise
Ft. Lauderdale → Buenos Aires/ARGENTINA
Wed, Nov 18 2026
Ft. Lauderdale, Grand Cayman, Panama Canal/CRUISING, Panama Canal/CRUISING, Fuerte Amador/PANAMA, Fuerte Amador/PANAMA, Manta/ECUADOR , Salaverry /PERU, Lima/PERU, Lima/PERU, General San Martin/PERU, Coquimbo/CHILE, San Antonio/CHILE, Puerto Montt/CHILE, Puerto Chacabuco/CHILE, Chilean Fjords, Pio Xi (Bruggen) Glacier, Punta Arenas/CHILE, Cockburn And Beagle Channels, Ushuaia/ARGENTINA, Stanley, Montevideo/URUGUAY , Buenos Aires/ARGENTINA, Buenos Aires/ARGENTINA
Call for rates
View Details
Majestic Princess
Onboard Majestic Princess
33-Night South America Cruise
Ft. Lauderdale → San Antonio/CHILE
Thu, Nov 19 2026
Ft. Lauderdale, St. Maarten, St. Lucia, Barbados, Fortaleza/BRAZIL, Rio De Janeiro/BRAZIL, Montevideo/URUGUAY , Buenos Aires/ARGENTINA, Buenos Aires/ARGENTINA, Buenos Aires/ARGENTINA, Montevideo/URUGUAY , Puerto Madryn/ARGENTINA, Stanley, Ushuaia/ARGENTINA, Cockburn And Beagle Channels, Punta Arenas/CHILE, Puerto Montt/CHILE, San Antonio/CHILE
Call for rates
View Details
Majestic Princess
Onboard Majestic Princess
18-Night South America Cruise
Ft. Lauderdale → Buenos Aires/ARGENTINA
Thu, Nov 19 2026
Ft. Lauderdale, St. Maarten, St. Lucia, Barbados, Fortaleza/BRAZIL, Rio De Janeiro/BRAZIL, Montevideo/URUGUAY , Buenos Aires/ARGENTINA, Buenos Aires/ARGENTINA
Call for rates
View Details
Silver Origin
Onboard Silver Origin
7-Night South America Cruise
Roundtrip · San Cristobal/ECUADOR
Sat, Nov 21 2026
San Cristobal/ECUADOR, El Barranco/genovesa Isl./ECUADOR, El Barranco/genovesa Isl./ECUADOR, Isla North Seymour/EQUADOR, Bahia Sullivan/santiago/ECUADOR, Isla Fernandina, Galapagos Islands, Isabela Isl./caleta Tagus/ECUADOR, Puerto Ayora/santa Cruz Isl./ECUADOR, Santa Cruz Isl./puerto Ayora/ECUADOR, Bahia Gardner/espanola Isl./EQUADOR, Punta Suarez/espanola/ECUADOR, Cerro Brujo, Galapagos Islands, San Cristobal/ECUADOR
Call for rates
View Details
Volendam
Onboard Volendam
30-Night South America Cruise
New York → Ft. Lauderdale
Sun, Nov 22 2026
New York, Ft. Lauderdale, St. Maarten, Martinique, Barbados, Macapa/BRAZIL, Santarem/BRAZIL, Boca Da Valeria/BRAZIL, Manaus/BRAZIL, Manaus/BRAZIL, Parintins/BRAZIL, Alter Do Chao/BRAZIL, Devil's Island/FR. GUIANA, Trinidad, Curacao, Ft. Lauderdale
Call for rates
View Details
Insignia
Onboard Insignia
25-Night South America Cruise
Roundtrip · Miami
Tue, Nov 24 2026
Miami, Tortola, Antigua , St. Lucia, Tobago, Santarem/BRAZIL, Boca Da Valeria/BRAZIL, Manaus/BRAZIL, Manaus/BRAZIL, Parintins/BRAZIL, Alter Do Chao/BRAZIL, Barbados, Dominica, St. Maarten, San Juan, Nassau, Miami
Call for rates
View Details
Saved to Maybe Trips