Need Help?
Panama Canal
Destination

Cruises to Panama Canal

140 sailings 9 cruise lines
All Months Sep '26 (2) Oct '26 (11) Nov '26 (6) Dec '26 (9) Jan '27 (15) Feb '27 (10) Mar '27 (11) Apr '27 (11) May '27 (1) Sep '27 (2) Oct '27 (8) Nov '27 (3) Dec '27 (8) Jan '28 (12) Feb '28 (4) Mar '28 (9) Apr '28 (7) Nov '28 (1) Dec '28 (3) Jan '29 (3) Feb '29 (3) Mar '29 (1)
All Sailings 140 Page 1 of 7
Carnival Miracle
Onboard Carnival Miracle
16-Night Panama Canal Cruise
Seattle → Galveston
Sat, Sep 26 2026
Seattle, Cabo San Lucas/MEXICO, Puntarenas/COSTA RICA, Panama Canal/CRUISING, Cartagena/COLOMBIA, Galveston
Call for rates
View Details
Nieuw Amsterdam
Onboard Nieuw Amsterdam
21-Night Panama Canal Cruise
Vancouver → Ft. Lauderdale
Sun, Sep 27 2026
Vancouver, San Francisco, San Diego, Puerto Vallarta/MEXICO, Huatulco/MEXICO, Puerto Chiapas/MEXICO, Puerto Quetzal/GUATEMALA, Acajutla/EL SALVADOR, Panama Canal/CRUISING, Panama Canal/CRUISING, Cartagena/COLOMBIA, Half Moon Cay, Ft. Lauderdale
Call for rates
View Details
Nieuw Amsterdam
Onboard Nieuw Amsterdam
16-Night Panama Canal Cruise
San Diego → Ft. Lauderdale
Fri, Oct 2 2026
San Diego, Puerto Vallarta/MEXICO, Huatulco/MEXICO, Puerto Chiapas/MEXICO, Puerto Quetzal/GUATEMALA, Acajutla/EL SALVADOR, Panama Canal/CRUISING, Panama Canal/CRUISING, Cartagena/COLOMBIA, Half Moon Cay, Ft. Lauderdale
Call for rates
View Details
Eurodam
Onboard Eurodam
21-Night Panama Canal Cruise
Seattle → Ft. Lauderdale
Sat, Oct 3 2026
Seattle, Vancouver, Santa Barbara, San Diego, Cabo San Lucas/MEXICO, Acapulco/MEXICO, Huatulco/MEXICO, Puerto Chiapas/MEXICO, Puerto Quetzal/GUATEMALA, Puntarenas/COSTA RICA, Panama Canal/CRUISING, Panama Canal/CRUISING, Aruba, Ft. Lauderdale
Call for rates
View Details
Eurodam
Onboard Eurodam
20-Night Panama Canal Cruise
Vancouver → Ft. Lauderdale
Sun, Oct 4 2026
Vancouver, Santa Barbara, San Diego, Cabo San Lucas/MEXICO, Acapulco/MEXICO, Huatulco/MEXICO, Puerto Chiapas/MEXICO, Puerto Quetzal/GUATEMALA, Puntarenas/COSTA RICA, Panama Canal/CRUISING, Panama Canal/CRUISING, Aruba, Ft. Lauderdale
Call for rates
View Details
Norwegian Joy
Onboard Norwegian Joy
16-Night Panama Canal Cruise
Los Angeles → Miami
Wed, Oct 7 2026
Los Angeles, Cabo San Lucas/MEXICO, Acapulco/MEXICO, Puerto Quetzal/GUATEMALA, Puerto Caldera/COSTA RICA, Panama City/PANAMA, Panama Canal/CRUISING, Cartagena/COLOMBIA, Ocho Rios, Miami
Call for rates
View Details
Carnival Spirit
Onboard Carnival Spirit
16-Night Panama Canal Cruise
Seattle → Mobile
Thu, Oct 8 2026
Seattle, Cabo San Lucas/MEXICO, Puntarenas/COSTA RICA, Panama Canal/CRUISING, Cartagena/COLOMBIA, Mobile
Call for rates
View Details
Eurodam
Onboard Eurodam
16-Night Panama Canal Cruise
San Diego → Ft. Lauderdale
Thu, Oct 8 2026
San Diego, Cabo San Lucas/MEXICO, Acapulco/MEXICO, Huatulco/MEXICO, Puerto Chiapas/MEXICO, Puerto Quetzal/GUATEMALA, Puntarenas/COSTA RICA, Panama Canal/CRUISING, Panama Canal/CRUISING, Aruba, Ft. Lauderdale
Call for rates
View Details
Norwegian Bliss
Onboard Norwegian Bliss
19-Night Panama Canal Cruise
Los Angeles → New York
Tue, Oct 13 2026
Los Angeles, Cabo San Lucas/MEXICO, Acapulco/MEXICO, Puerto Quetzal/GUATEMALA, Puerto Caldera/COSTA RICA, Panama City/PANAMA, Panama Canal/CRUISING, Cartagena/COLOMBIA, Falmouth/JAMAICA, Miami, New York
Call for rates
View Details
Norwegian Bliss
Onboard Norwegian Bliss
16-Night Panama Canal Cruise
Los Angeles → Miami
Tue, Oct 13 2026
Los Angeles, Cabo San Lucas/MEXICO, Acapulco/MEXICO, Puerto Quetzal/GUATEMALA, Puerto Caldera/COSTA RICA, Panama City/PANAMA, Panama Canal/CRUISING, Cartagena/COLOMBIA, Falmouth/JAMAICA, Miami
Call for rates
View Details
Nieuw Amsterdam
Onboard Nieuw Amsterdam
12-Night Panama Canal Cruise
Roundtrip · Ft. Lauderdale
Sun, Oct 18 2026
Ft. Lauderdale, Half Moon Cay, Aruba, Cartagena/COLOMBIA, Panama Canal/CRUISING, Panama Canal/gatun Lake/PANAMA, Panama Canal/CRUISING, Colon/PANAMA, San Jose/COSTA RICA, Grand Cayman, Ft. Lauderdale
Call for rates
View Details
Nieuw Amsterdam
Onboard Nieuw Amsterdam
21-Night Panama Canal Cruise
Roundtrip · Ft. Lauderdale
Sun, Oct 18 2026
Ft. Lauderdale, Half Moon Cay, Aruba, Cartagena/COLOMBIA, Panama Canal/CRUISING, Panama Canal/gatun Lake/PANAMA, Panama Canal/CRUISING, Colon/PANAMA, San Jose/COSTA RICA, Grand Cayman, Ft. Lauderdale, Cabo Rojo, Dominican Republic, Curacao, Aruba, Half Moon Cay, Ft. Lauderdale
Call for rates
View Details
Nieuw Amsterdam
Onboard Nieuw Amsterdam
21-Night Panama Canal Cruise
Roundtrip · Ft. Lauderdale
Fri, Oct 30 2026
Ft. Lauderdale, Cabo Rojo, Dominican Republic, Curacao, Aruba, Half Moon Cay, Ft. Lauderdale, Half Moon Cay, Aruba, Cartagena/COLOMBIA, Panama Canal/CRUISING, Panama Canal/gatun Lake/PANAMA, Panama Canal/CRUISING, Colon/PANAMA, San Jose/COSTA RICA, Ocho Rios, Ft. Lauderdale
Call for rates
View Details
Disney Magic
Onboard Disney Magic
14-Night Panama Canal Cruise
San Diego → Galveston
Fri, Nov 6 2026
San Diego, Cabo San Lucas/MEXICO, Puerto Vallarta/MEXICO, Panama Canal/CRUISING, Cartagena/COLOMBIA, Grand Cayman, Galveston
Call for rates
View Details
Norwegian Sun
Onboard Norwegian Sun
12-Night Panama Canal Cruise
Roundtrip · Miami
Fri, Nov 6 2026
Miami, Great Stirrup Cay, Cabo Rojo, Dominican Republic, Curacao, Aruba, Panama Canal/gatun Lake/PANAMA, Colon/PANAMA, San Jose/COSTA RICA, Grand Cayman, Miami
Call for rates
View Details
Nieuw Amsterdam
Onboard Nieuw Amsterdam
12-Night Panama Canal Cruise
Roundtrip · Ft. Lauderdale
Sun, Nov 8 2026
Ft. Lauderdale, Half Moon Cay, Aruba, Cartagena/COLOMBIA, Panama Canal/CRUISING, Panama Canal/gatun Lake/PANAMA, Panama Canal/CRUISING, Colon/PANAMA, San Jose/COSTA RICA, Ocho Rios, Ft. Lauderdale
Call for rates
View Details
Nieuw Amsterdam
Onboard Nieuw Amsterdam
21-Night Panama Canal Cruise
Roundtrip · Ft. Lauderdale
Sun, Nov 8 2026
Ft. Lauderdale, Half Moon Cay, Aruba, Cartagena/COLOMBIA, Panama Canal/CRUISING, Panama Canal/gatun Lake/PANAMA, Panama Canal/CRUISING, Colon/PANAMA, San Jose/COSTA RICA, Ocho Rios, Ft. Lauderdale, Bonaire, Curacao, Curacao, Half Moon Cay, Ft. Lauderdale
Call for rates
View Details
Norwegian Sun
Onboard Norwegian Sun
11-Night Panama Canal Cruise
Roundtrip · Miami
Wed, Nov 18 2026
Miami, Great Stirrup Cay, Cartagena/COLOMBIA, Panama Canal/gatun Lake/PANAMA, Colon/PANAMA, San Jose/COSTA RICA, Falmouth/JAMAICA, Grand Cayman, Miami
Call for rates
View Details
Norwegian Sun
Onboard Norwegian Sun
11-Night Panama Canal Cruise
Roundtrip · Miami
Sun, Nov 29 2026
Miami, Great Stirrup Cay, Cartagena/COLOMBIA, Panama Canal/gatun Lake/PANAMA, Colon/PANAMA, San Jose/COSTA RICA, Falmouth/JAMAICA, Grand Cayman, Miami
Call for rates
View Details
Norwegian Star
Onboard Norwegian Star
16-Night Panama Canal Cruise
Miami → San Diego
Fri, Dec 4 2026
Miami, Cartagena/COLOMBIA, Colon/PANAMA, Panama Canal/CRUISING, Puntarenas/COSTA RICA, Puerto Quetzal/GUATEMALA, Acapulco/MEXICO, Puerto Vallarta/MEXICO, Cabo San Lucas/MEXICO, San Diego
Call for rates
View Details
Saved to Maybe Trips