Day 1 : Istanbul/TURKEY

Once called Constantinople, the former capital of the Byzantine Empire is the only city in the world to straddle two continents: Europe and Asia. This is the Golden Horn, the door between East and West, and your first vision of its domes and minarets is unforgetable. Hagia Sophia, the Blue Mosque and Sultan treasures in Topkapi Palace await - as does the Grand Bazaar, laden with carpets, beaten brass and spices from afar.

Day 2 :

Dikili is the port for the ancient mountain citadel of Pergamum where you can visit Asklepeion, the site where psychiatry was first practiced. Also see the Sacred Pools, the Altar of Zeus, the Library, and the Serpent Altar which still serves as the symbol of the medical profession.

Day 3 : Izmir

Day 4 : Athens/GREECE

Piraeus is the seaport for Athens, the capital of western civilization, which boasts a fantastic mix of classical ruins and vivacious modern life. In a single day, you can climb the hill of the Acropolis to wonder at the Parthenon, join the lively Athenians in Constitution Square, and then find a welcoming taverna for some spirited bizouki music, plenty of ouzo to drink, and with luck, energetic Greek dancing.

Day 5 : At Sea

Day 6 : Messina/ITALY

The setting for Shakespeare's Much Ado About Nothing, Messina has much to offer in the way of history. Its dramatic, boulder-filled harbor has challenged navigators since the days of Ulysses. Try to visit the city's Bell Tower at the stroke of noon--the hour when one of the world's largest and most fanciful mechanical clocks springs into action. Messina's museum is also noteworthy for its Renaissance masterworks.

Day 7 : Naples/ITALY

One of the most spectacular bays in the world lies in the shadow of Mt. Vesuvius. Visit the San Carlo Opera House and the cathedral of San Janarious, or tour the ancient ruins in the Roman cities of Pompeii and Herculaneum.

Day 8 : Florence/pisa/ITALY

The achievements of the Renaissance have been preserved and lovingly cared for by the city...artists like Botticelli and Michelangelo were encouraged to produce masterpieces like the Birth of Venus and David. Advancements in architecture, the likes of which hadn't been seen before in Europe... But before you think that Florence is a city trapped in the past, know that it is a highly modernized Italian town...Florence has also emerged as one of the leading shopping and dining destinations in Italy

Day 9 : Nice/FRANCE

This village of 7,000 inhabitants is hidden among wooded slopes, above the crystalline waters of the Cote d'Azure. The town itself is delightful, with medieval chapels and an impressive hilltop fortress built by the Duke of Savoy in 1560. And, just up the coast are the luxuries of Nice and the extravagance of Monte Carlo.

Day 10 : Marseille/FRANCE

Marseille is France's second largest city, but it often goes unnoticed and unvisited by travelers... They are missing out on one of France's most diverse cities, both in terms of people and activities... Today, Marseille faces the same problems as any growing city. Crime is an issue, as is racial tension between the native French population and the arriving North African immigrants. Twenty-five percent of the population in Marseille is of North African descent, and that number is growing. But the city has come to embrace its newfound diversity, and is eager to put its best foot forward to attract a piece of the ever-growing tourism industry.

Day 11 : Barcelona/SPAIN

Barcelona is the cultural heartland of Spain, yet its first language is Catalan, the native tongue of the proudly independent Catalonia region. Stroll down the shady, tree-lined Ramblas between street musicians and elegant bistros. Then perhaps visit the venerable Gothic cathedral, Picasso Museum or enjoy the architectural genius of Antonio Gaudi's Church of the Holy Family.