Day 1 : Rome/ITALY

The port of Civitavecchia is the gateway to The Eternal City, where all roads lead. Mad traffic careens past monuments of the great civilizations of the past. You will want to see it all: the soaring inspiration of St. Peter's, the Vatican and the Sistine Chapel; the flow of life along the Spanish Steps, the Coliseum, the Via Veneto and Trevi Fountain. Be sure to leave time for la dolce vita in one of the piazzas.

Day 2 : Amalfi Coast/ITALY

Day 3 : Palermo/ITALY

Once regarded as Europe's grandest, most beautiful city, Palermo is still quite impressive. The Four Corners of Palermo, where each 17th-century Spanish Baroque facade is adorned with a statue, is one of the city's most memorable sights. The Fontana Pretoria, often called the Fountain of Shame because of its nude Florentine figures, is also worth noting. Tour the famous Norman Cathedral and Capuchin catacombs. A day trip to Monreale to see the famous 12th-century cathedral is also recommended.

Day 4 : Valletta/MALTA

The Knights of St. John made this their base in the Mediterranean Sea. The castles, cathedrals and fortresses they built still are their remaining legacy. But Phoenicians, Romans, Carthaginians and Arabs preceded them and left their marks as well. Take a drive to M''dina, the former capital, and wonder at Europe''s third-largest dome in Mostra.

Day 5 : At Sea

Day 6 : Agios Nikolaos

Also spelt Ayios Nikolaos. On the Isle of Crete.

Day 7 : Marmaris/TURKEY

Day 8 : Antalya

This fortified seaport was already centuries old when St. Paul and St. Barnabas left its harbor on their journey to Antioch. Explore the superb museum in a converted Byzantine church, visit the ancient Roman Theatre, or simply relax amid the pleasant scents of orange groves and pine forests. Those hungry for more history can venture to the ancient towns of Side and Perge.

Day 9 : Kos/GREECE

Kos is known as the home of Hippocrates, father of medical science. The town is an archeological repository of Archaic, Classical, Hellenistic, and Roman ruins. Take a tour to the ancient Asklepeion and the island's archaeological museum.

Day 10 : Santorini/GREECE

With its steep volcanic flanks looming straight up from the sea, and the tiny white village of Thira clinging high atop the cliffs, Santorini is perhaps the most breathtaking and legendary of all the Greek Isles. To the south is Akrotiri, where recent Minoan excavations support the theories that Santorini might be the fabled lost continent of Atlantis.

Day 11 : Izmir

Day 12 : Istanbul/TURKEY

Once called Constantinople, the former capital of the Byzantine Empire is the only city in the world to straddle two continents: Europe and Asia. This is the Golden Horn, the door between East and West, and your first vision of its domes and minarets is unforgetable. Hagia Sophia, the Blue Mosque and Sultan treasures in Topkapi Palace await - as does the Grand Bazaar, laden with carpets, beaten brass and spices from afar.

Day 13 : Istanbul/TURKEY

Once called Constantinople, the former capital of the Byzantine Empire is the only city in the world to straddle two continents: Europe and Asia. This is the Golden Horn, the door between East and West, and your first vision of its domes and minarets is unforgetable. Hagia Sophia, the Blue Mosque and Sultan treasures in Topkapi Palace await - as does the Grand Bazaar, laden with carpets, beaten brass and spices from afar.